Tetrahydrofuran
English Name: tetrahydrofuran
Chinese alias: oxyheterocyclopentane; Oxyamyl ring; Anhydrous tetrahydrofuran; Tetrahydroxycene; Tetramethylene oxide; 1,4-epoxy butane; Tetramethyleneoxide
English alias: THF; tetrahydrofuran; oxolane; Sodium tri-sec-butylborohydride; Butane, alpha,delta-oxide;
Cyclotetramethylene oxide; Diethylene oxide; Furan, tetrahydro-; Furanidine; 1,2,3,4-tetrahydro-9H-fluoren-9-one
CAS No.: 109-99-9
Molecular formula: C4H? O
Molecular weight: 72.11
EINECS No.: 203-786-5
1. Used as solvent and raw material for organic synthesis.
2. Used as chromatographic reagent, organic solvent and nylon 66 intermediate. Tetrahydrofuran, also known as monocyclopentadecane, oxyheterocyclopentane and tetramethylene oxygen, is an intermediate for the synthesis of pesticide phenylbutyltin. In addition, it can be directly used to prepare synthetic fiber, synthetic resin and synthetic rubber. It is also a solvent for many polymeric materials, precision tape and electroplating industries. It is also used to prepare adiponitrile, adipic acid, hexamethylene diamine, succinic acid, butanediol γ- Butyrolactone can be used to produce kebiqing, progesterone, rifamycin and pharmaceutical solvent in the pharmaceutical industry.
3. Tetrahydrofuran is an important organic synthetic raw material and a solvent with excellent performance. It is especially suitable for dissolving PVC, polyvinylidene chloride and butyniline. It is widely used as a solvent for surface coating, anti-corrosion coating, printing ink, tape and film coating, and as a reaction solvent. When it is used for electroplating aluminum solution, it can arbitrarily control the thickness and brightness of aluminum layer. Tetrahydrofuran itself can be polycondensated (ring opening polymerization initiated by cation) to form poly tetramethylene ether glycol (PTMEG), also known as tetrahydrofuran homopolyether. PTMEG and toluene diisocyanate (TDI) are made into special rubber with wear resistance, oil resistance, good low temperature performance and high strength; Block polyether polyester elastic material was prepared with dimethyl terephthalate and 1,4-butanediol. PTMEG with relative molecular weight of 2000 and p-methylene bis (4-phenyl) diisocyanate (MDI) are raw materials for polyurethane elastic fiber (spandex fiber), special rubber and some special-purpose coatings. In organic synthesis, it is used to produce Tetrahydrothiophene, 1.2-dichloroethane, 2.3-dichlorotetrahydrofuran, pentalactone, butyrolactone and pyrrolidone. In the pharmaceutical industry, THF is used to synthesize kebiqing, rifamycin, progesterone and some hormone drugs. THF is treated with hydrogen sulfide to produce tetrahydrothiophenol, which can be used as odorant (identification additive) in fuel gas. THF can also be used as a surface treatment agent for synthetic leather.